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Sticky mouse : ウィキペディア英語版 | Sticky mouse Sticky mouse is a murine mutant possessing a defective alanyl-tRNA synthetase (AARS) and therefore used in investigational studies into mechanisms of neuronal degeneration. Its most immediately obvious symptom is a sticky secretion on the mouse's fur (thus the name); however, it is accompanied by lack of muscle control, ataxia, alopecia, loss of Purkinje cells in the cerebellum, and eventually, death. Sticky mouse is one of several animal mutants that are known to have problems in mRNA translation and are used in studies. == See also ==
* Wasted mouse (wst) - EEF1A2 defect * Harlequin mouse * Reeler - RELN defect * Shaking rat Kawasaki - RELN defect
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Sticky mouse」の詳細全文を読む
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